Guale Indians. The Indian name by which the Spaniards knew the present Amelia island, north coast of Florida, and a part of the adjacent Florida and Georgia coast, in the 16th century. There is strong probability that the tribe in occupancy was that known later as Yamasi. In 1597 the son of the chief of Guale led a revolt against the missions that had been established by the Spanish Franciscans a few years before. There were then on the island at least 3 mission villages, Asao, Asopo, and Ospo. The missions were re-established in 1605 and may have continued until their destruction by the English and their Indian allies in 1704-06.
For Further Study:
The following articles and manuscripts will shed much more light on the Guale as both an ethnological study, and as a people.