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William Clyce, of Virginia, was an early settler near Pinckney, in Warren County. He married Nancy Hart, and they had Milford, Elizabeth, and Preston. His first wife died, and he was married the second time to Polly Wyatt, by whom he had Nancy, Frank, William, Gabriella, and Thomas. Milford married in Kentucky, to Priscilla Williams. Elizabeth married and settled in Linn County, Missouri. Preston and Frank died single, in Kentucky. Nancy married a Mr. Swasey, of Canada, who settled at Pinckney, in Warren County, and opened a store. William married Christina Cheeseman, a German lady. Gabriella married Cunningham Parsons. Thomas married Rebecca Anderson, and lives in High Hill, Missouri.