Spiers Singleton was the son of George Singleton, of North Carolina. He married Lucinda Whitesides, of Christian Co., Ky., and settled in Illinois, where he died, leaving a widow and seven children. Her brother, James Whitesides, brought her and the children to Montgomery County, and attended to their wants until the children were grown, and at his death he left most of his property to them. The names of the children were James W., Ewell D., John S., Emeline, Cynthia A., Polly, and Mary A.