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Matthew Busby, of Ireland, was a weaver by trade. He came to America and settled first in Delaware, from whence he removed to Bath Co., Ky., at an early date. He had seven sons, one of whom, James, married Nancy Lewis, of Delaware, by whom he had eleven children Isaac, Rolley, John, James, Hiram, Lewis, Granville, Elizabeth, Lucretia, Amanda, and Malinda. Lewis and James settled in Missouri. The former married Eliza McClannahan, of Kentucky, and settled in Missouri in 1835.