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Weanoc Indians. A tribe of the Powhatan confederacy, formerly living in Charles City County, Virginia, on the north bank of James river. In 1608 they numbered about 500. They seem to have crossed over to the south bank of James river toward the close of the 17th century, perhaps in consequence of a disastrous attack from the Iroquois in 1687. In 1722 Beverley stated that their former settlement in Prince George county, south of the James, was extinct, and in 1727 it was stated that they had lived at different times on upper Nottoway river and on a tributary stream, then called Wyanoke creek, near the North Carolina frontier. Nottoway river was also at one time known by their name.